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Long-term outcomes in children on chronic continuous ambulatory peritoneal dialysis: a retrospective cohort study from a developing country.
- Source :
- Pediatric Nephrology; Nov2019, Vol. 34 Issue 11, p2389-2397, 9p, 1 Diagram, 2 Charts, 3 Graphs
- Publication Year :
- 2019
-
Abstract
- Background: Peritoneal dialysis (PD) is the preferred modality of dialysis among children with end-stage renal disease. Methods: To study the incidence of technique failure and survival among children with end-stage renal disease on continuous ambulatory peritoneal dialysis (CAPD), we included children younger than 18 years of age who commenced and continued PD for more than 3 months as their primary form of dialysis between 1st January 2005 and 31st December 2016. Kaplan–Meier survival analysis was applied to analyze the CAPD outcomes. Results: A total of 68 Tenckhoff (58 double cuffs, and ten single cuffs) catheters were inserted in 66 patients (mean age 12.3 ± 3.91 years) during the study period. Of the 66 children, 31 (47%) experienced 45 episodes of peritonitis. The total duration on CAPD was 107.58 years with a peritonitis rate of 0.42 episodes per year. Overall, the mean patient survival was 41 (95% confidence interval (CI) 29–54) months, with mean patient survival of 72% at 12 months, declining to 30% at 36 months and then remaining stable until the end of follow-up (106 months). The overall mean technique survival was 55 (95% CI 40–69) months, with mean technique survival of 69% at 12 months, declining to 44% at 36 months and then remaining stable until the end of follow-up (106 months). Conclusion: CAPD is a viable option for end-stage renal disease in children from developing countries with a lack of access to automated PD and pediatric hemodialysis centers. [ABSTRACT FROM AUTHOR]
- Subjects :
- TREATMENT of chronic kidney failure
CHILDREN'S health
CHILDREN'S hospitals
CHRONIC kidney failure
CONFIDENCE intervals
CONTINUOUS ambulatory peritoneal dialysis
DEVELOPING countries
HEALTH services accessibility
HEMODIALYSIS facilities
LONGITUDINAL method
PERITONITIS
ADOLESCENT health
TREATMENT effectiveness
DISEASE incidence
RETROSPECTIVE studies
TREATMENT duration
DIALYSIS catheters
KAPLAN-Meier estimator
DISEASE risk factors
EVALUATION
Subjects
Details
- Language :
- English
- ISSN :
- 0931041X
- Volume :
- 34
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Pediatric Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 139138158
- Full Text :
- https://doi.org/10.1007/s00467-019-04311-w