Purification and Characterization of Atopic Allergens.

The article focuses on purification and characterization of atopic allergens. In the past two decades, several atopic allergens, which induce IgE antibody-mediated immediate hypersensitivity in man have been purified to near homogeneity and studied for their immunochemical properties. In this paper will be reviewed some of the general findings drawn from such studies. Allergen characterization studies with extracts from these sources have confirmed the views of allergists that all extracts are multi-allergen systems and that individuals can have varying patterns of sensitivity to different allergens.