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Pretreatment of mice with anti-IgD serum does not result in suppression of immune responsiveness induced by TNP-AECM-Ficoll or lipopolysaccharide.
- Source :
- Immunology; Mar1983, Vol. 48 Issue 3, p497-501, 5p
- Publication Year :
- 1983
-
Abstract
- Unlike the suppression of a primary response to a thymus-dependent antigen, pretreatment of mice with anti-IgD serum has no effect on the response to a thymus-independent (TI) antigen. It has also been shown that anti-IgD serum injected parenterally into mice 2 days previously, has no suppressive effect on non-specific responsiveness to an intraperitoneal injection of LPS. There is a similar lack of effect on the non-specific element of responsiveness to a TI antigen. These results provide in vivo confirmation of the results of previous in vitro experimentation. [ABSTRACT FROM AUTHOR]
- Subjects :
- ANTIGENS
IMMUNOGLOBULIN D
IMMUNOGLOBULINS
IMMUNOLOGY
T cells
B cells
Subjects
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 48
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 13944723