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Activation of non-specific cytotoxic cells in <em>Listeria</em>-susceptible and -resistant mouse strains.

Authors :
Wood, P.
Cheers, Christina
Source :
Immunology; Jan1985, Vol. 54 Issue 1, p113-119, 7p
Publication Year :
1985

Abstract

An increase in macrophage tumouricidal activity in the spleen was demonstrated following intravenous infection of genetically resistant C57BL/10 mice with Listeria monocytogenes, but not after infection of BALB/c mice. However, tumouricidal macrophages appeared in the peritoneal cavity of both strains after infection, while NK cell activity was generally higher in BALB/c mice. The activation of tumouricidal macrophages and NK cells in the C57BL/B10 mice was T independent and, at least in the peritoneal cavity, radioresistant (600 rads). The relevance of these results to the genetic control of resistance to Listeria is discussed. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00192805
Volume :
54
Issue :
1
Database :
Complementary Index
Journal :
Immunology
Publication Type :
Academic Journal
Accession number :
13948621