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Efficacy of Magnifying Narrow Band Imaging for Delineating Horizontal Margins of Early Gastric Cancer.
- Source :
- Digestion; Aug2019, Vol. 100 Issue 2, p93-99, 7p, 1 Color Photograph, 1 Diagram, 3 Charts
- Publication Year :
- 2019
-
Abstract
- Background/Aims: The aim of this study was to evaluate the diagnostic accuracy of magnifying narrow-band imaging (M-NBI) with histopathological confirmation in identifying the demarcation line (DL) of early gastric cancer (EGC). Methods: EGCs resected by endoscopic submucosal dissection after identifying the DL using M-NBI following histopathological confirmation were included. After determining the DL for the entire EGC lesion using M-NBI, at least 4 biopsies were taken from non-cancerous tissues outside the EGC lesion for histopathological confirmation. Results: A total of 330 EGCs were analyzed in this study. The rate of biopsy-negative and negative horizontal margin were 96.7% (319/330) and 97.9% (323/330) in EGC respectively. Tumors larger than 20 mm showed a higher risk for showing remnant cancer cells on biopsies taken outside the DL. Risk factors for a positive horizontal resection margin were tumor size > 20 mm and moderately or poorly differentiated adenocarcinomas. Conclusion: The assessment of demarcation of EGC using M-NBI was excellent in well-differentiated (WD) adenocarcinoma and lesions below 20 mm in size. However, histopathological confirmation is needed to assess the demarcation of non-WD adenocarcinomas and EGC over 20 mm in size. [ABSTRACT FROM AUTHOR]
- Subjects :
- STOMACH cancer
DISEASE risk factors
CANCER cells
TUMORS
Subjects
Details
- Language :
- English
- ISSN :
- 00122823
- Volume :
- 100
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Digestion
- Publication Type :
- Academic Journal
- Accession number :
- 139565243
- Full Text :
- https://doi.org/10.1159/000494053