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The influence of T cells on the initiation and expression of immunological memory.
- Source :
- Immunology; Oct79, Vol. 38 Issue 2, p265-274, 10p
- Publication Year :
- 1979
-
Abstract
- Nude and normal CBA mice have been used in adoptive transfer experiments to analyse the development of immunological memory. The development of B-cell memory to xenogeneic erythrocyte antigens is to a very large degree dependent on the presence of T cells, wit h IgG memory being somewhat more dependent than IgM memory. In this system, the expression of B memory, that is the transformation of memory cells to antibody-secreting cells under the inductive influence of antigen, is largely dependent on the presence of T cells. Primed (educated) T cells can have an antigen-specific potentiating effect on unprimed B cells in the presence of antigen. [ABSTRACT FROM AUTHOR]
- Subjects :
- IMMUNOLOGIC memory
IMMUNITY
IMMUNOLOGY
T cells
LYMPHOCYTES
CELLS
Subjects
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 38
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 13986030