Back to Search
Start Over
Quantitative, Multi-institutional Evaluation of MR Thermometry Accuracy for Deep-Pelvic MR-Hyperthermia Systems Operating in Multi-vendor MR-systems Using a New Anthropomorphic Phantom.
- Source :
- Cancers; Nov2019, Vol. 11 Issue 11, p1709-1709, 1p
- Publication Year :
- 2019
-
Abstract
- Clinical outcome of hyperthermia depends on the achieved target temperature, therefore target conformal heating is essential. Currently, invasive temperature probe measurements are the gold standard for temperature monitoring, however, they only provide limited sparse data. In contrast, magnetic resonance thermometry (MRT) provides unique capabilities to non-invasively measure the 3D-temperature. This study investigates MRT accuracy for MR-hyperthermia hybrid systems located at five European institutions while heating a centric or eccentric target in anthropomorphic phantoms with pelvic and spine structures. Scatter plots, root mean square error (RMSE) and Bland–Altman analysis were used to quantify accuracy of MRT compared to high resistance thermistor probe measurements. For all institutions, a linear relation between MRT and thermistor probes measurements was found with R<superscript>2</superscript> (mean ± standard deviation) of 0.97 ± 0.03 and 0.97 ± 0.02, respectively for centric and eccentric heating targets. The RMSE was found to be 0.52 ± 0.31 °C and 0.30 ± 0.20 °C, respectively. The Bland-Altman evaluation showed a mean difference of 0.46 ± 0.20 °C and 0.13 ± 0.08 °C, respectively. This first multi-institutional evaluation of MR-hyperthermia hybrid systems indicates comparable device performance and good agreement between MRT and thermistor probes measurements. This forms the basis to standardize treatments in multi-institution studies of MR-guided hyperthermia and to elucidate thermal dose-effect relations. [ABSTRACT FROM AUTHOR]
- Subjects :
- PELVIC radiography
SPINE radiography
CARDIOVASCULAR disease diagnosis
COMPARATIVE studies
HEALTH facilities
HEATING
INFORMATION storage & retrieval systems
MEDICAL databases
DOSE-response relationship (Radiation)
MAGNETIC resonance imaging
MEDICAL cooperation
MEDICAL thermography
MEDICAL thermometers
NUCLEAR magnetic resonance spectroscopy
IMAGING phantoms
QUALITY assurance
RADIO waves
MEDICAL radiology
RESEARCH
THERMOTHERAPY
QUANTITATIVE research
Subjects
Details
- Language :
- English
- ISSN :
- 20726694
- Volume :
- 11
- Issue :
- 11
- Database :
- Complementary Index
- Journal :
- Cancers
- Publication Type :
- Academic Journal
- Accession number :
- 139863512
- Full Text :
- https://doi.org/10.3390/cancers11111709