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Suppression of induced erythrocyte autoantibodies is dependent on Lyt 1 cells.
- Source :
- Immunology; Oct85, Vol. 56 Issue 2, p269-273, 5p
- Publication Year :
- 1985
-
Abstract
- When normal mice are immunized with rat RBC, autoantibodies to mouse red cells and antigen-specific suppressor cells are generated. Suppressor cell activity is found in T-enriched populations and suppresses only the induction of autoantibody, not ongoing or secondary autoantibody responses. Using anti- bodies lytic for either B cells or distinct T-cell subpopulations, we are able to show that suppression is dependent on the presence of Lyt 1<superscript> +</superscript> T cells. [ABSTRACT FROM AUTHOR]
- Subjects :
- ERYTHROCYTES
BLOOD cells
AUTOANTIBODIES
IMMUNOGLOBULINS
SUPPRESSOR cells
T cells
Subjects
Details
- Language :
- English
- ISSN :
- 00192805
- Volume :
- 56
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 14003711