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Inula viscosa (L.) Aiton leaves and flower buds: Effect of extraction solvent/technique on their antioxidant ability, antimicrobial properties and phenolic profile.
- Source :
- Natural Product Research; Jan2020, Vol. 34 Issue 1, p46-52, 7p
- Publication Year :
- 2020
-
Abstract
- This study was designed to establish the most effective solvent/technique for extracting antioxidant phytoconstituents from leaves and flower buds of Inula viscosa (L.) Aiton (Asteraceae) grown wild in Morocco. Maceration and hot extraction with methanol or water and Soxhlet ethanol extraction were utilized. The antioxidant potential was evaluated in vitro by DPPH, reducing power, and ferrous ions chelating activity assays. I. viscosa leaf and flower bud extracts displayed the strongest effect in the DPPH test, being the Soxhlet ethanol the most active ones (IC<subscript>50</subscript> = 54.24 ± 0.21 μg/mL and 39.77 ± 0.23 μg/mL); thus, they were selected for further investigations. The antimicrobial efficacy of the Soxhlet ethanol extracts against ATCC and food isolates strains was assayed; the leaf extract showed the best activity, and Candida albicans was the most sensitive strain (MIC = 125 µg/mL). The extracts resulted non-toxic against Artemia salina. Among the phenolics characterised by HPLC-PDA-ESI-MS, hispidulin hexoside, patuletin and spinacetin were identified for the first time. [ABSTRACT FROM AUTHOR]
- Subjects :
- SOLVENT extraction
IRON ions
BUDS
CANDIDA albicans
FLOWERS
Subjects
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 34
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 140974168
- Full Text :
- https://doi.org/10.1080/14786419.2019.1569659