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Update 2020: nomenclature and listing of celiac disease–relevant gluten epitopes recognized by CD4+ T cells.
- Source :
- Immunogenetics; Feb2020, Vol. 72 Issue 1/2, p85-88, 4p
- Publication Year :
- 2020
-
Abstract
- Celiac disease is caused by an abnormal intestinal T cell response to cereal gluten proteins. The disease has a strong human leukocyte antigen (HLA) association, and CD4<superscript>+</superscript> T cells recognizing gluten epitopes presented by disease-associated HLA-DQ allotypes are considered to be drivers of the disease. This paper provides an update of the currently known HLA-DQ restricted gluten T cell epitopes with their names and sequences. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00937711
- Volume :
- 72
- Issue :
- 1/2
- Database :
- Complementary Index
- Journal :
- Immunogenetics
- Publication Type :
- Academic Journal
- Accession number :
- 141292300
- Full Text :
- https://doi.org/10.1007/s00251-019-01141-w