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Spectrum of Newly Diagnosed Cytomegalovirus Retinitis in a Developing Country in the HAART Era.
- Source :
- Ocular Immunology & Inflammation; 2020, Vol. 28 Issue 1, p119-125, 7p
- Publication Year :
- 2020
-
Abstract
- Purpose: To characterize the presenting features of cytomegalovirus (CMV) retinitis in HIV-positive patients in a developing country in the HAART era.Methods: Retrospective chart review of all patients with CMV retinitis seen at a tertiary-care referral center between January 2006 to June 2017. Demographic and clinical data were collected to study the presenting features and risk factors for blindness.Results: Fifty-five patients with treatment-naïve CMV retinitis were enrolled; 75% were males. CD4 counts were below 50 cells/µL in 51.1%. Bilateral presentation was seen in 61.5%. Half (50.6%) of the eyes were blind at first examination. Zone 1 involvement was present in 46% of the eyes. Retinal area involvement > 25% was the only factor associated significantly with higher incidence of blindness (p = 0.016).Conclusions: There was extensive and bilateral presentation of CMV retinitis due to delayed presentation. Screening for CMV retinitis, irrespective of CD4 counts, may help in developing nations. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09273948
- Volume :
- 28
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Ocular Immunology & Inflammation
- Publication Type :
- Academic Journal
- Accession number :
- 141627294
- Full Text :
- https://doi.org/10.1080/09273948.2018.1538460