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A self-powered 3D DNA walker with programmability and signal-amplification for illuminating microRNA in living cells.

Authors :
Yang, Xue-Jiao
Cui, Mei-Rong
Li, Xiang-Ling
Chen, Hong-Yuan
Xu, Jing-Juan
Source :
Chemical Communications; 2/18/2020, Vol. 56 Issue 14, p2135-2138, 4p
Publication Year :
2020

Abstract

Based on the structural programmability and spatial addressability of DNA nanodevices, a target-triggered, enzyme-free 3D DNA walker, comprising of hairpin DNA assembled gold nanoparticles with a local catalytic hairpin assembly reaction, was developed for the highly sensitive detection of intracellular tumor-associated microRNAs. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
56
Issue :
14
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
141804610
Full Text :
https://doi.org/10.1039/c9cc09039h