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Association between neutropenia and IgG antineutrophil antibodies in a case of CD40LG deficiency due to two novel mutations.
- Source :
- Clinical Case Reports; Feb2020, Vol. 8 Issue 2, p313-316, 4p
- Publication Year :
- 2020
-
Abstract
- This case suggests a mechanistic rationale for the clinical efficacy of intravenous immunoglobulins (IVIG) in treating CD40 ligand (CD40L) deficiency associated neutropenia as it is the first reported instance of free and cell‐bound antineutrophil antibodies in a case of CD40L deficiency, accompanied by a prolonged and clinically severe neutropenia. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20500904
- Volume :
- 8
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Clinical Case Reports
- Publication Type :
- Academic Journal
- Accession number :
- 141934857
- Full Text :
- https://doi.org/10.1002/ccr3.2621