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Mass cytometry in POEMS (polyneuropathy, organomegaly, endocrinopathy, Māprotein, skin changes) syndrome: looking for a needle in a haystack.
- Source :
- British Journal of Haematology; Jul2020, Vol. 190 Issue 1, p16-17, 2p
- Publication Year :
- 2020
-
Abstract
- Mass cytometry in POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) syndrome: looking for a needle in a haystack In their current paper, Kourelis I et al i . profile the different immune cells within the bone marrow (BM) of patients with POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes) (Kourelis I et al. i , [8]). Different immune checkpoint regulators are expressed by HRS cells, but PD-L1 is found to be universally present on HRS cells due to a genetic amplification at chromosome 9 (De Goycoechea I et al. i , [6]). [Extracted from the article]
Details
- Language :
- English
- ISSN :
- 00071048
- Volume :
- 190
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- British Journal of Haematology
- Publication Type :
- Academic Journal
- Accession number :
- 144299619
- Full Text :
- https://doi.org/10.1111/bjh.16554