Risk of major depressive disorder in spouses of cancer patients in Japan: A cohort study using health insurance-based claims data.

Keywords: administrative claims, healthcare; cancer; depressive disorder, major; epidemiology; oncology; spouses EN administrative claims, healthcare cancer depressive disorder, major epidemiology oncology spouses 1224 1227 4 07/04/20 20200701 NES 200701 Key Points Using a Japanese medical insurance database, we determined the risk of major depressive disorder (MDD) in spouses of newly diagnosed cancer patients compared with patients and with spouses of cancer-free individuals. We measured the time to MDD diagnosis from 6 months before to 12 months after the index month in cancer patients with spouses, in the spouses of those cancer patients, in cancer-free individuals with spouses, and in the spouses of those cancer-free individuals. DISCUSSION In this Japanese database analysis, spouses of cancer patients were at elevated risk of MDD diagnosis compared with spouses of cancer-free individuals, but at approximately half the risk of cancer patients. [Extracted from the article]