Recurrent Pulmonary Fibrosis in a Lung Allograft Secondary to Antisynthetase Syndrome.

The article describes the case of a 51-year-old female with recurrent nonspecific interstitial pneumonia of the fibrotic pattern (NSIP-F) in the lung allograft and manifested de novo clinical and serological features of antisynthetase syndrome after bilateral lung transplantation for advanced idiopathic fibrotic NSIP. Topics discussed include progressive pulmonary fibrosis, connective tissue disease-associated interstitial lung disease, and treatment with hydroxychloroquine and rituximab.