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The diffuse-type gastric cancer epidemiology enigma.
- Source :
- BMC Gastroenterology; 7/13/2020, Vol. 20 Issue 1, p1-7, 7p, 2 Diagrams, 1 Chart
- Publication Year :
- 2020
-
Abstract
- <bold>Background: </bold>Intestinal and diffuse gastric adenocarcinomas differ in clinical, epidemiological and molecular features. However, most of the concepts related to the intestinal-type are translated to gastric adenocarcinoma in general; thus, the peculiarities of the diffuse-type are underappreciated.<bold>Results: </bold>Besides its growing importance, there are many gaps about the diffuse-type carcinogenesis and, as a result, its epidemiologic and pathogenetic features remain poorly understood.<bold>Conclusions: </bold>Alternative hypotheses to explain these features are discussed, including the role of the gastric microbiota, medical therapies, and modifications in the stomach's microenvironment. [ABSTRACT FROM AUTHOR]
- Subjects :
- EPIDEMIOLOGY of cancer
STOMACH cancer
RIDDLES
STOMACH
CARCINOGENESIS
Subjects
Details
- Language :
- English
- ISSN :
- 1471230X
- Volume :
- 20
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- BMC Gastroenterology
- Publication Type :
- Academic Journal
- Accession number :
- 144545767
- Full Text :
- https://doi.org/10.1186/s12876-020-01354-4