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PM2.5 air pollution contributes to the burden of frailty.
- Source :
- Scientific Reports; 9/2/2020, Vol. 10 Issue 1, pN.PAG-N.PAG, 1p
- Publication Year :
- 2020
-
Abstract
- Frailty is common among older people and results in adverse health outcomes. We investigated whether exposure to PM<subscript>2.5</subscript> is associated with frailty. This cross-sectional study involved 20,606 community-dwelling participants aged ≥ 65 years, residing in New Taipei City, Taiwan. Analytic data included phenotypic frailty, disease burden by Charlson Comorbidity Index (CCI), urban or rural residence, and household income. PM<subscript>2.5</subscript> exposure was calculated from air quality monitoring records, with low exposure defined as the lowest quartile of the study population. 1,080 frail participants (5.2%) were older, predominantly female, had more comorbidities, lived rurally, and had low PM<subscript>2.5</subscript> exposure (all p < 0.001). In multinomial logistic regression analyses, the likelihood of high PM<subscript>2.5</subscript> exposure was higher in prefrail (OR 1.4, 95% CI 1.3–1.5) and frail adults (OR 1.5, 95% CI 1.2–1.9) than in robust individuals, with stronger associations in those who were male (frail: OR 2.1, 95% CI 1.5–3.1; prefrail: OR 2.2, 95% CI 1.9–2.6), ≥ 75 years old (frail: OR 1.8, 95% CI 1.3–2.4; prefrail: OR 1.5, 95% CI 1.3–1.8), non-smokers (frail: OR 1.6, 95% CI 1.3–2.0; prefrail: OR 1.4, 95% CI 1.2–1.5), had CCI ≥ 2 (frail: OR 5.1, 95% CI 2.1–12.6; prefrail: OR 2.1, 95% CI 1.2–3.8), and with low household income (frail: OR 4.0, 95% CI 2.8–5.8; prefrail: OR 2.7, 95% CI 2.2–3.3). This study revealed a significant association between PM<subscript>2.5</subscript> exposure and frailty, with a stronger effect in vulnerable groups. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20452322
- Volume :
- 10
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Scientific Reports
- Publication Type :
- Academic Journal
- Accession number :
- 145675490
- Full Text :
- https://doi.org/10.1038/s41598-020-71408-w