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Investigation of phase-contrast magnetic resonance imaging underestimation of turbulent flow through the aortic valve phantom: experimental and computational study using lattice Boltzmann method.

Authors :
Fučík, Radek
Galabov, Radek
Pauš, Petr
Eichler, Pavel
Klinkovský, Jakub
Straka, Robert
Tintěra, Jaroslav
Chabiniok, Radomír
Source :
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine; Oct2020, Vol. 33 Issue 5, p649-662, 14p
Publication Year :
2020

Abstract

Objective: The accuracy of phase-contrast magnetic resonance imaging (PC-MRI) measurement is investigated using a computational fluid dynamics (CFD) model with the objective to determine the magnitude of the flow underestimation due to turbulence behind a narrowed valve in a phantom experiment. Materials and methods: An acrylic stationary flow phantom is used with three insertable plates mimicking aortic valvular stenoses of varying degrees. Positive and negative horizontal fluxes are measured at equidistant slices using standard PC-MRI sequences by 1.5T and 3T systems. The CFD model is based on the 3D lattice Boltzmann method (LBM). The experimental and simulated data are compared using the Bland-Altman-derived limits of agreement. Based on the LBM results, the turbulence is quantified and confronted with the level of flow underestimation. Results: LBM gives comparable results to PC-MRI for valves up to moderate stenosis on both field strengths. The flow magnitude through a severely stenotic valve was underestimated due to signal void in the regions of turbulent flow behind the valve, consistently with the level of quantified turbulence intensity. Discussion: Flow measured by PC-MRI is affected by noise and turbulence. LBM can simulate turbulent flow efficiently and accurately, it has therefore the potential to improve clinical interpretation of PC-MRI. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09685243
Volume :
33
Issue :
5
Database :
Complementary Index
Journal :
MAGMA: Magnetic Resonance Materials in Physics, Biology & Medicine
Publication Type :
Academic Journal
Accession number :
145976735
Full Text :
https://doi.org/10.1007/s10334-020-00837-5