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Bioactive triterpenoids from Sambucus javanica Blume.
- Source :
- Natural Product Research; Oct2020, Vol. 34 Issue 19, p2816-2821, 6p
- Publication Year :
- 2020
-
Abstract
- A new triterpene, javablumine A (1) along with six known ones were isolated from the aerial parts of Sambucus javanica Blume. They were identified as 3β,23-dihydroxy-11α,12α-epoxy-urs-20(30)-en-28,13β-olide (1), ursolic acid (2), pomolic acid (3), oleanic acid (4), 2α-hydroxy-oleanolic acid (5), α-amyrin (6), and lupeol palmitate (7), respectively. Compounds 1 and 3 exhibited inhibitory effect against nitric oxide (NO) production in lipopolysaccharide (LPS)-activated RAW264.7 macrophage cell lines with IC<subscript>50</subscript> values of 17.4 and 26.2 μM, respectively. [ABSTRACT FROM AUTHOR]
- Subjects :
- TRITERPENOIDS
URSOLIC acid
CELL lines
NITRIC oxide
Subjects
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 34
- Issue :
- 19
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 146196356
- Full Text :
- https://doi.org/10.1080/14786419.2019.1596092