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FGFR3 Alterations in the Era of Immunotherapy for Urothelial Bladder Cancer.

Authors :
Kacew, Alec
Sweis, Randy F.
Source :
Frontiers in Immunology; 11/5/2020, Vol. 11, pN.PAG-N.PAG, 5p
Publication Year :
2020

Abstract

FGFR3 is a prognostic and predictive marker and is a validated therapeutic target in urothelial bladder cancer. Its utility as a marker and target in the context of immunotherapy is incompletely understood. We review the role of FGFR3 in bladder cancer and discuss preclinical and clinical clues of its effectiveness as a patient selection factor and therapeutic target in the era of immunotherapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16643224
Volume :
11
Database :
Complementary Index
Journal :
Frontiers in Immunology
Publication Type :
Academic Journal
Accession number :
146822246
Full Text :
https://doi.org/10.3389/fimmu.2020.575258