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Executive summary of clinical practice guide on fracture risk in lifestyle diseases.

Authors :
Kanazawa, Ippei
Inaba, Masaaki
Inoue, Daisuke
Uenishi, Kazuhiro
Saito, Mitsuru
Shiraki, Masataka
Suzuki, Atsushi
Takeuchi, Yasuhiro
Hagino, Hiroshi
Fujiwara, Saeko
Sugimoto, Toshitsugu
Source :
Journal of Bone & Mineral Metabolism; Nov2020, Vol. 38 Issue 6, p746-758, 13p
Publication Year :
2020

Abstract

Accumulating evidence has shown that patients with lifestyle diseases such as type 2 diabetes mellitus, chronic kidney disease, and chronic obstructive pulmonary disease are at increased risk of osteoporotic fracture. Fractures deteriorate quality of life, activities of daily living, and mortality as well as a lifestyle disease. Therefore, preventing fracture is an important issue for those patients. Although the mechanism of the lifestyle diseases-induced bone fragility is still unclear, not only bone mineral density (BMD) reduction but also bone quality deterioration are involved in it. Because fracture predictive ability of BMD and FRAX<superscript>®</superscript> is limited, especially for patients with lifestyle diseases, the optimal management strategy should be established. Thus, when the intervention of the lifestyle diseases-induced bone fragility is initiated, the deterioration of bone quality should be taken into account. We here review the association between lifestyle diseases and fracture risk and proposed an algorism of starting anti-osteoporosis drugs for patients with lifestyle diseases. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
09148779
Volume :
38
Issue :
6
Database :
Complementary Index
Journal :
Journal of Bone & Mineral Metabolism
Publication Type :
Academic Journal
Accession number :
146870442
Full Text :
https://doi.org/10.1007/s00774-020-01149-3