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A self-accelerated biocatalyst for glucose-initiated tumor starvation and chemodynamic therapy.

Authors :
Deng, Fuan
Fan, Guiling
Yuan, Ping
Liu, Yibin
Huang, Chuyu
Zhao, Linping
Wang, Xin
Yu, Xiyong
Cheng, Hong
Li, Shiying
Source :
Chemical Communications; 12/4/2020, Vol. 56 Issue 93, p14633-14636, 4p
Publication Year :
2020

Abstract

A self-accelerated biocatalyst (Bio-Cat) was developed based on BSA and GOx crosslinked nanoproteins for glucose-initiated tumor starvation and chemodynamic therapy. Bio-Cat could catalyze the glucose to elevate the intracellular H<subscript>2</subscript>O<subscript>2</subscript> level and accelerate the conversion of Fe<superscript>3+</superscript>/Fe<superscript>2+</superscript>, resulting in an effective starvation therapy and an accelerated Fenton reaction for chemodynamic therapy. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13597345
Volume :
56
Issue :
93
Database :
Complementary Index
Journal :
Chemical Communications
Publication Type :
Academic Journal
Accession number :
147174844
Full Text :
https://doi.org/10.1039/d0cc06483a