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Templated insertions at VD and DJ junctions create unique B‐cell receptors in the healthy B‐cell repertoire.
- Source :
- European Journal of Immunology; Dec2020, Vol. 50 Issue 12, p2099-2101, 3p
- Publication Year :
- 2020
-
Abstract
- Templated insertions at VD and DJ junctions create unique B-cell receptors in the healthy B-cell repertoire RAG complexes recognise (cryptic) RSS sites both in and outside immunoglobulin sites. GLO:BVO/01dec20:eji4896-gra-0001.jpg PHOTO (COLOR): . gl RAG-mediated rearrangement of B- and T-cell receptor (BCR; TCR) gene loci is a unique genetic mechanism to generate a highly diverse antigen receptor repertoire. [Extracted from the article]
- Subjects :
- IMMUNOGLOBULIN class switching
ANTIGEN receptors
B cells
Subjects
Details
- Language :
- English
- ISSN :
- 00142980
- Volume :
- 50
- Issue :
- 12
- Database :
- Complementary Index
- Journal :
- European Journal of Immunology
- Publication Type :
- Academic Journal
- Accession number :
- 147547571
- Full Text :
- https://doi.org/10.1002/eji.202048828