Templated insertions at VD and DJ junctions create unique B‐cell receptors in the healthy B‐cell repertoire.

Templated insertions at VD and DJ junctions create unique B-cell receptors in the healthy B-cell repertoire RAG complexes recognise (cryptic) RSS sites both in and outside immunoglobulin sites. GLO:BVO/01dec20:eji4896-gra-0001.jpg PHOTO (COLOR): . gl RAG-mediated rearrangement of B- and T-cell receptor (BCR; TCR) gene loci is a unique genetic mechanism to generate a highly diverse antigen receptor repertoire. [Extracted from the article]