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Metal‐Free Selective and Diverse Synthesis of Three Distinct Sets of Isoindolinones from 2‐Alkynylbenzoic Acids and Amines.
- Source :
- European Journal of Organic Chemistry; 12/20/2020, Vol. 2020 Issue 47, p7343-7357, 15p
- Publication Year :
- 2020
-
Abstract
- The metal‐free selective and diverse synthesis of three distinct sets of isoindolinones from 2‐alkynylbenzoic acids and amines has been achieved in a reaction‐condition‐controlled manner. This method exhibits valuable advantageous features such as available starting materials, broad substrate scope, excellent selectivity, good to high yields, good functional group tolerance, simple operation, high bond‐forming efficiency, and step economy, thus providing a convenient and efficient access to a variety of heterocyclic compounds incorporating the bioactive isoindolinone motif. [ABSTRACT FROM AUTHOR]
- Subjects :
- BIOACTIVE compounds
AMINES
HETEROCYCLIC compounds
FUNCTIONAL groups
ACIDS
Subjects
Details
- Language :
- English
- ISSN :
- 1434193X
- Volume :
- 2020
- Issue :
- 47
- Database :
- Complementary Index
- Journal :
- European Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 147673766
- Full Text :
- https://doi.org/10.1002/ejoc.202001413