Bidirectional longitudinal associations of fatness with physical fitness in adolescents with Down syndrome. The UP&DOWN Longitudinal study.

Background: The aim of this study was to examine the bidirectional longitudinal associations of several markers of fatness and physical fitness in adolescents with Down syndrome. Methods: This study comprised a total of 111 adolescents (41 females), aged from 11 to 20 years with complete data at the baseline. We had a drop‐out of <10% from the baseline to the 2‐year follow‐up. The ALPHA health‐related fitness test battery for youth was used. Results: Our results show that all fatness variables at the baseline were associated with a 2‐year change in cardiorespiratory fitness (β ranging from −0.32 to −0.38; all p <.05), but not with muscular and motor fitness (p >.05). However, no associations were found between physical fitness components as predictors and fatness indicators (p >.05). Conclusions: Results suggest that reducing fatness during adolescence might represent a modifiable factor to improve cardiorespiratory fitness at the 2‐year follow‐up, but not vice versa since associations were not bidirectional. [ABSTRACT FROM AUTHOR]