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Biomechanical correlates of sequential drinking behavior in aging.

Authors :
Cock, Charles
Omari, Taher I.
Burgstad, Carly M.
Thompson, Alison
Doeltgen, Sebastian H.
Source :
Neurogastroenterology & Motility; Jan2021, Vol. 33 Issue 1, p1-10, 10p
Publication Year :
2021

Abstract

Background: The timed water swallow test (TWST) is a test of sequential swallowing where a measured volume is ingested as quickly as comfortably possible. We undertook a study of the biomechanics underpinning the TWST in healthy young and older participants. Methods: Thirty healthy volunteers underwent high‐resolution impedance manometry (MMS; Unisensor, 2.7 mm diameter, 32 pressure sensors, 16 impedance segments). Participants were asked to drink 150 mL, 0.9% normal saline solution rapidly. Swallowing biomechanics and bolus flow characteristics were assessed using pressure‐flow analysis and compared using t test and Fisher's exact test with significance as P <.05. Key Results: Older participants (n = 18; 76 ± 11 years) took longer to complete the TWST (21.2 ± 2.5 vs 9.2 ± 1.0 seconds; P <.001) and displayed reduced volume per swallow (16.6 ± 1.3 vs 27.8 ± 2.9 mL; P <.001) compared to younger participants (n = 12; 29 ± 5 years). Two distinctive pharyngeal swallowing patterns were observed: (a) a single rapid sequence of swallows with or without a clearing swallow (Pattern I) or (b) multiple, shorter sequences interrupted and/or interspersed with single swallows or breaks (Pattern II). Some older participants showed biomechanical evidence of upper esophageal sphincter restriction (n = 7) or impaired deglutitive inhibition (n = 7), associated with the more prolonged Pattern II (TWST duration 30.1 ± 1.5 vs Pattern I 11.9 ± 1.5 seconds; P <.001). Conclusions and Inferences: Healthy older participants had an increased duration of TWST, suggesting a need to adapt normative values for this population. Rapid sequential swallowing was associated with evidence of UES restriction and impaired deglutitive inhibition in some older participants. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13501925
Volume :
33
Issue :
1
Database :
Complementary Index
Journal :
Neurogastroenterology & Motility
Publication Type :
Academic Journal
Accession number :
147826573
Full Text :
https://doi.org/10.1111/nmo.13945