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ROLE OF COMBINED KETOCONAZOLE AND TAMSULOSIN IN SUCCESSFUL TRIAL OF VOIDING WITHOUT CATHETER (TWOC) IN PATIENTS WITH ACUTE URINARY RETENTION DUE TO BENIGN PROSTATIC OBSTRUCTION.
- Source :
- Pakistan Armed Forces Medical Journal; Dec2020, Vol. 70 Issue 6, p1723-1727, 5p
- Publication Year :
- 2020
-
Abstract
- Objective: To compare the frequency of patients with successful trial of voiding without catheter after acute urinary retention secondary to benign prostatic hyperplasia in patients taking ketoconazole and tamsulosin vs tamsulosin alone. Study Design: A quasi-experimental study. Place and Duration of Study: Urology Ward, Liaquat National Hospital, Pakistan, from Jul 2016 to Jan 2017. Methodology: A total of 162 patients presenting with acute urinary retention were divided into two groups. Group A received tamsulosin 0.4mg OD and ketoconazole 200mg while group B received tamsulosin and placebo. Trial of voiding without a catheter was induced after one week of medication. Results: In group-A, 69 (85.2%) of patients were able to void as compared to group B, where only 60 (74.1%) of patients were able to void (p=0.05). Successful trial of voiding without catheter was observed in 64 (79%) and 49 (60.5%) in patients of group-A and group-B respectively. The association of successful trial of voiding without catheter with the two study groups was found significant (p=0.010). Conclusion: Trial of voiding without catheter in men catheterized for acute urinary retention due to benign prostatic hyperplasia was significantly more successful if treated in combination of ketoconazole and tamsulosin as compared to tamsulosin only. [ABSTRACT FROM AUTHOR]
- Subjects :
- RETENTION of urine
TAMSULOSIN
KETOCONAZOLE
BENIGN prostatic hyperplasia
CATHETERS
Subjects
Details
- Language :
- English
- ISSN :
- 00309648
- Volume :
- 70
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Pakistan Armed Forces Medical Journal
- Publication Type :
- Academic Journal
- Accession number :
- 147954224
- Full Text :
- https://doi.org/10.51253/pafmj.v70i6.3913