Could a rabies incursion spread in the northern Australian dingo population? Development of a spatial stochastic simulation model.

Australia, home to the iconic dingo, is currently free from canine rabies. However northern Australia, including Indigenous communities with large free-roaming domestic dog populations, is at increased risk of rabies incursion from nearby Indonesia. We developed a novel agent-based stochastic spatial rabies spread model to evaluate the potential spread of rabies within the dingo population of the Northern Peninsula Area (NPA) region of northern Australia. The model incorporated spatio-temporal features specific to this host-environment system, including landscape heterogeneity, demographic fluctuations, dispersal movements and dingo ecological parameters—such as home range size and density—derived from NPA field studies. Rabies spread between dingo packs in nearly 60% of simulations. In such situations rabies would affect a median of 22 dingoes (approximately 14% of the population; 2.5–97.5 percentiles: 2–101 dingoes) within the study area which covered 1,131 km², and spread 0.52 km/week for 191 days. Larger outbreaks occurred in scenarios in which an incursion was introduced during the dry season (vs. wet season), and close to communities (vs. areas with high risk of interaction between dingoes and hunting community dogs). Sensitivity analyses revealed that home range size and duration of infectious clinical period contributed most to the variance of outputs. Although conditions in the NPA would most likely not support a sustained propagation of the disease in the dingo population, due to the predicted number of infected dingoes following a rabies incursion and the proximity of Indigenous communities to dingo habitat, we conclude that the risk for human transmission could be substantial. Author summary: Although Australia is free from canine rabies, an incursion from nearby rabies-infected Indonesian islands is a realistic threat. The ubiquitous presence of dingoes in the wild, in association with large populations of free-roaming domestic dogs from northern Australian Indigenous communities, increases the risk of a rabies outbreak. Using a newly developed simulation model, we investigated the potential spread of rabies in a northern Australian dingo population. Nearly 60% of model simulations resulted in more than one pack infected. When spread did occur, outbreaks affected a median of 22 dingoes (an estimated 14% of the population in this area). The duration of infection, proportion of the population infected and spatial spread of the outbreak was greatest when rabies was introduced during the dry season and close to communities. Our results demonstrate that an incursion of rabies into the northern Australian dingo population would likely lead to a rabies outbreak, which would in turn pose a substantial threat to Indigenous communities in northern Australia. [ABSTRACT FROM AUTHOR]