IiISTOPATHOLOGICAL ALTERATIONS IN LUNGS OF MALE SWISS ALBINO MICE AFTER 28 DAYS CARTAPEXPOSURE.

Cartap is a synthetic insecticide of thiocarbamates group and extensively used in agriculture to control rice stem borer and several other pests. Cartapinduced histopathological changes in lungs are yet to be studied in vivo. Present study was undertaken to evaluate the cartap induced histopathological changes in lungs after subacute oral exposure in mice. Mice were divided into four groups containing control and treatment groups. Mice in the treatment groups were exposed to the different doses of cartap, i.e. 5 mg/kg, 7.5 mg/kg and 15 mg/kg bw. respectively for 28 days. Thus, the result of present study demonstrated that in vivo exposure to cartap induce severe and prominent histopathological alterations in lungs of mice. [ABSTRACT FROM AUTHOR]