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COVID‐19 and hepatic involvement: The liver as a main actor of the pandemic novel.

Authors :
Napodano, Cecilia
Pocino, Krizia
Stefanile, Annunziata
Marino, Mariapaola
Miele, Luca
Gulli, Francesca
Basile, Valerio
Pandolfi, Franco
Gasbarrini, Antonio
Rapaccini, Gian Ludovico
Basile, Umberto
Source :
Scandinavian Journal of Immunology; Mar2021, Vol. 93 Issue 3, p1-8, 8p
Publication Year :
2021

Abstract

In the natural history of SARS‐CoV‐2 infection, liver injury is frequent but quite mild and it is defined as any liver damage occurring during disease progression and treatment of infection in patients with or without pre‐existing liver diseases. The underlying mechanisms for hepatic injury in patients with COVID‐19 are still unclear but the liver damage in SARS‐CoV‐2 infection seems to be directly caused by virus‐induced cytopathic effects. In this review, we will summarize all data of updated literature, regarding the relationship between SARS‐CoV‐2 infection, acute response and liver involvement. An overview will be given on liver injury, liver transplant and the possible consequences of COVID‐19 in patients with pre‐existing liver diseases. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03009475
Volume :
93
Issue :
3
Database :
Complementary Index
Journal :
Scandinavian Journal of Immunology
Publication Type :
Academic Journal
Accession number :
148885539
Full Text :
https://doi.org/10.1111/sji.12977