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Transition-Metal-Catalyzed Cross-Coupling Reactions of Grignard Reagents.
- Source :
- Synthesis; 2021, Vol. 53 Issue 6, p983-1002, 20p
- Publication Year :
- 2021
-
Abstract
- Transition-metal-catalyzed cross-coupling of organo-halides, ethers, sulfides, amines, and alcohols (and derivatives thereof) with Grignard reagents, known as the Kumada–Tamao–Corriu reaction, can be used to prepare important intermediates in the synthesis of numerous- biologically active compounds. The most frequently used transition metals are nickel, palladium, and iron, but there are several examples for cross-coupling reactions catalyzed by copper, cobalt, manganese, chromium, etc. salts and complexes. The aim of this review is to summarize the most important transition-metal-catalyzed cross-coupling reactions realized in the period 2000 to 2020. 1 Introduction 2 Nickel Catalysis 3 Palladium Catalysis 4 Iron Catalysis 5 Catalysis by Other Transition Metals 5.1 Cobalt Catalysis 5.2 Copper Catalysis 5.3 Manganese Catalysis 5.4 Chromium Catalysis 6 Conclusion [ABSTRACT FROM AUTHOR]
- Subjects :
- GRIGNARD reagents
PALLADIUM
BIOACTIVE compounds
TRANSITION metals
CHROMIUM
MANGANESE
Subjects
Details
- Language :
- English
- ISSN :
- 00397881
- Volume :
- 53
- Issue :
- 6
- Database :
- Complementary Index
- Journal :
- Synthesis
- Publication Type :
- Academic Journal
- Accession number :
- 148946615
- Full Text :
- https://doi.org/10.1055/s-0040-1705986