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Cotard syndrome in anti-NMDAR encephalitis: two patients and insights from molecular imaging.
- Source :
- Neurocase (Taylor & Francis Ltd); Feb2021, Vol. 27 Issue 1, p64-71, 8p
- Publication Year :
- 2021
-
Abstract
- Cotard syndrome is a clinical condition defined by the presence of nihilistic delusions. We report two patients with Cotard syndrome in whom anti-NMDAR encephalitis (ANMDARE) was confirmed. Both cases showed features of affective psychosis, developed catatonic syndrome, and worsened after the use of antipsychotics. 18F-FDG PET brain studies showed a bilateral hemispheric pattern of hypometabolism in posterior regions, mainly in the cingulate cortex and in the medial aspects of parietal and occipital lobes. A more severe hypometabolism was observed in the right hemisphere of both patients. Both cases remitted with the use of specific immunotherapy for ANMDARE. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13554794
- Volume :
- 27
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Neurocase (Taylor & Francis Ltd)
- Publication Type :
- Academic Journal
- Accession number :
- 149693270
- Full Text :
- https://doi.org/10.1080/13554794.2020.1866018