Back to Search
Start Over
A porphysome-based photodynamic O2 economizer for hypoxic tumor treatment by inhibiting mitochondrial respiration.
- Source :
- Chemical Communications; 4/30/2021, Vol. 57 Issue 34, p4134-4137, 4p
- Publication Year :
- 2021
-
Abstract
- A porphysome-based photodynamic O<subscript>2</subscript> economizer (P-PAT) is prepared for hypoxic tumor therapy. The self-assembled porphyrin bilayers of P-PAT possess high loading capacity to atovaquone (ATO) (nearly 70%), which could restrain mitochondrial respiration to relieve hypoxia and enhance photodynamic therapy. [ABSTRACT FROM AUTHOR]
- Subjects :
- TUMOR treatment
MITOCHONDRIA
PHOTODYNAMIC therapy
RESPIRATION
PORPHYRINS
HYPOXEMIA
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 57
- Issue :
- 34
- Database :
- Complementary Index
- Journal :
- Chemical Communications
- Publication Type :
- Academic Journal
- Accession number :
- 150036381
- Full Text :
- https://doi.org/10.1039/d1cc00544h