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Correlation between Sarcopenia and Arteriosclerosis in Elderly Community Dwellers: A Multicenter Study.
- Source :
- Journal of Nutrition, Health & Aging; May2021, Vol. 25 Issue 5, p692-697, 6p
- Publication Year :
- 2021
-
Abstract
- Background: Evidence suggests that arteriosclerosis and sarcopenia (decreased muscle mass) share some of their many causes. However, after controlling for confounding factors, it is unclear whether the presence of arteriosclerosis correlates with sarcopenia. Objectives: The aim of this paper is to explore whether sarcopenia is associated with arteriosclerosis. Design: A multicenter cross-sectional community-based study. Materials and methods: A total of 2511 elderly subjects from six Chinese community health service centers in Anhui province were surveyed through an e-health promotion system to collect basic data and measurements of brachial-ankle pulse wave (baPWV), body composition, and handgrip strength (HGS). Pearson's correlation and binary logistic regression analyses were performed to identify associations between sarcopenia and high baPWV. Results: The prevalence rates of sarcopenia were 12.9% in men and 15.3% in women according to the 2019 standard of Asian Working Group for Sarcopenia. Among subjects with high baPWV, the proportion of sarcopenia was higher compared to those with normal baPWV (men: 17.7% vs. 3.7%; women: 20.4% vs. 4.9%, both p<0.001). Binary logistic regression analysis revealed that sarcopenia was associated with high baPWV (p<0.0001, odds ratio=1.619) after adjusting for confounding factors. HGS slightly and negatively correlated with baPWV (−0.19 in men and −0.18 in women). Conclusions: The intertwined pathophysiological mechanisms shared by arteriosclerosis and sarcopenia are potential targets for future interventions to reduce morbimortality in subjects with both disorders. Upcoming prospective studies and clinical trials are expected to advance these findings. [ABSTRACT FROM AUTHOR]
- Subjects :
- ARTERIOSCLEROSIS risk factors
RESEARCH
BODY composition
GRIP strength
BLOOD pressure
CONFIDENCE intervals
CROSS-sectional method
SARCOPENIA
MEDICAL cooperation
RISK assessment
SURVEYS
INDEPENDENT living
QUESTIONNAIRES
DISEASE prevalence
DESCRIPTIVE statistics
STATISTICAL correlation
LOGISTIC regression analysis
ODDS ratio
OLD age
Subjects
Details
- Language :
- English
- ISSN :
- 12797707
- Volume :
- 25
- Issue :
- 5
- Database :
- Complementary Index
- Journal :
- Journal of Nutrition, Health & Aging
- Publication Type :
- Academic Journal
- Accession number :
- 150128354
- Full Text :
- https://doi.org/10.1007/s12603-021-1624-4