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AGREEing on clinical practice guidelines for idiopathic steroid-sensitive nephrotic syndrome in children.

Authors :
Alhasan, Khalid Abdulaziz
Al Khalifah, Reem
Aloufi, Majed
Almaiman, Weiam
Hamad, Muddathir
Abdulmajeed, Naif
Al Salloum, Abdullah
Kari, Jameela A.
AlJelaify, Muneera
Bassrawi, Rolan K.
Al Hussain, Turki
Alherbish, Adi
Al Talhi, Abdulhadi
Temsah, Mohamad-Hani
Sethi, Sidharth Kumar
Raina, Rupesh
Joseph, Reny
Amer, Yasser Sami
Source :
Systematic Reviews; 5/10/2021, Vol. 10 Issue 1, p1-12, 12p
Publication Year :
2021

Abstract

Background: Nephrotic syndrome is the most common kidney disease in children worldwide. Our aim was to critically appraise the quality of recent Clinical Practice Guidelines (CPGs) for idiopathic steroid-sensitive nephrotic syndrome (SSNS) in children in addition to summarize and compare their recommendations. Methods: Systematic review of CPGs. We identified clinical questions and eligibility criteria and searched and screened for CPGs using bibliographic and CPG databases. Each included CPG was assessed by four independent appraisers using the Appraisal of Guidelines for REsearch & Evaluation II (AGREE-II) instrument. We summarized the recommendations in a comparison practical table. Results: Our search retrieved 282 citations, of which three CPGs were eligible and appraised: Kidney Disease: Improving Global Outcomes (KDIGO) 2012, Japan Society for Pediatric Nephrology (JSPN) 2014, and American Academy of Pediatrics (AAP) 2009. Among these, the overall assessment of two evidence-based CPGs scored > 70% (KDIGO and JSPN), which was consistent with their higher scores in the six domains of the AGREE II Instrument. In domain 3 (rigor of development), KDIGO, JSPN, and AAP scored 84%, 74%, and 41%, respectively. In domain 5 (applicability), they scored 22%, 16%, and 19%, respectively, and in domain 6 (editorial independence), they scored 94%, 65%, and 88%, respectively. Conclusions: The methodological quality of the KDIGO CPG was superior, followed by JSPN and AAP CPGs with the relevant recommendations for use in practice. Systematic review registration: The protocol was registered in the Center for Open Science (OSF) DOI: 10.17605/OSF.IO/6QTMD and in the International prospective register of systematic reviews PROSPERO 2020 CRD42020197511. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20464053
Volume :
10
Issue :
1
Database :
Complementary Index
Journal :
Systematic Reviews
Publication Type :
Academic Journal
Accession number :
150234767
Full Text :
https://doi.org/10.1186/s13643-021-01666-w