Editorial: Glial Cells, Maladaptive Plasticity, and Neurodegeneration: Mechanisms, Targeted Therapies, and Future Directions.

Keywords: glial cells; neuroinflammation; neurodegeneration; synaptic homeostasis; synaptic plasticity EN glial cells neuroinflammation neurodegeneration synaptic homeostasis synaptic plasticity N.PAG N.PAG 4 05/17/21 20210430 NES 210430 Understanding the biological complexity of the central nervous system (CNS) is a frontier in neuroscience. Regional brain susceptibility to neurodegeneration: what is the role of glial cells? Glial cells, neuroinflammation, neurodegeneration, synaptic homeostasis, synaptic plasticity Recently, it has been hypothesized that the morpho-functional heterogeneity of astrocytes in different brain regions might explain the regional diversity of astrocytic response to an external injury and the selectivity of neuronal degeneration (Cragnolini et al., [7], [6]). [Extracted from the article]