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Should COVID-19 patients >75 years be Ventilated? An Outcome Study.
- Source :
- QJM: An International Journal of Medicine; Mar2021, Vol. 114 Issue 3, p182-189, 8p
- Publication Year :
- 2021
-
Abstract
- Background Elderly patients with COVID-19 disease are at increased risk for adverse outcomes. Current data regarding disease characteristics and outcomes in this population are limited. Aim To delineate the adverse factors associated with outcomes of COVID-19 patients ≥75 years of age. Design Retrospective cohort study. Methods Patients were classified into mild/moderate, severe/very severe and critical disease (intubated) based on oxygen requirements. The primary outcome was in-hospital mortality. Results A total of 355 patients aged ≥75 years hospitalized with COVID-19 between 19 March and 25 April 2020 were included.Mean age was 84.3 years. One-third of the patients developed critical disease. Mean length of stay was 7.10 days. Vasopressors were required in 27%, with the highest frequency in the critical disease group (74.1%). Overall mortality was 57.2%, with a significant difference between severity groups (mild/moderate disease: 17.4%, severe/very severe disease: 71.3%, critical disease: 94.9%, P < 0.001).Increased age, dementia, and severe/very severe and critical disease groups were independently associated with increased odds for mortality while diarrhea was associated with decreased odds for mortality (OR: 0.12, 95% CI: 0.02–0.60, P < 0.05). None of the cardiovascular comorbidities were significantly associated with mortality. Conclusion Age and dementia are associated with increased odds for mortality in patients ≥75 years of age hospitalized with COVID-19. Those who require intubation have the greatest odds for mortality. Diarrhea as a presenting symptom was associated with lower odds for mortality. [ABSTRACT FROM AUTHOR]
- Subjects :
- COVID-19
OLDER patients
HOSPITAL mortality
DEMENTIA
COHORT analysis
Subjects
Details
- Language :
- English
- ISSN :
- 14602725
- Volume :
- 114
- Issue :
- 3
- Database :
- Complementary Index
- Journal :
- QJM: An International Journal of Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 150746378
- Full Text :
- https://doi.org/10.1093/qjmed/hcab029