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COVID-19 Infection in Children, Infants and Pregnant Subjects: An Overview of Recent Insights and Therapies.
- Source :
- Microorganisms; Sep2021, Vol. 9 Issue 9, p1964, 1p
- Publication Year :
- 2021
-
Abstract
- Background: The SARS-CoV-2 pandemic has involved a severe increase of cases worldwide in a wide range of populations. The aim of the present investigation was to evaluate recent insights about COVID-19 infection in children, infants and pregnant subjects. Methods: a literature overview was performed including clinical trials, in vitro studies, reviews and published guidelines regarding the present paper topic. A descriptive synthesis was performed to evaluate recent insights and the effectiveness of therapies for SARS-CoV-2 infection in children, infants and pregnant subjects. Results: Insufficient data are available regarding the relationship between COVID-19 and the clinical risk of spontaneous abortion and premature foetus death. A decrease in the incidence of COVID-19 could be correlated to a minor expression of ACE2 in childrens' lungs. At present, a modulation of the dose-effect posology for children and infants is necessary. Conclusions: Pregnant vertical transmission has been hypothesised for SARS-CoV-2 infection. Vaccines are necessary to achieve mass immunity for children and also pregnant subjects. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 20762607
- Volume :
- 9
- Issue :
- 9
- Database :
- Complementary Index
- Journal :
- Microorganisms
- Publication Type :
- Academic Journal
- Accession number :
- 152690859
- Full Text :
- https://doi.org/10.3390/microorganisms9091964