A Novel Antigen, Otubain Cysteine Peptidase of Leishmania donovani, for the Serodiagnosis of Visceral Leishmaniasis and for Monitoring Treatment Response.

Authors :: Kamran, Mohd
Ejazi, Sarfaraz Ahmad
Choudhury, Somsubhra Thakur
Bhattacharyya, Anirban
Tanishka, Km
Pandey, Krishna
Das, Vidya Nand Ravi
Das, Pradeep
Silva, Fernando Oliveira da
Costa, Dorcas Lamounier
Costa, Carlos Henrique Nery
Rahaman, Mehebubar
Goswami, Rama Prosad
Ali, Nahid
Source :: Clinical Infectious Diseases; 10/1/2021, Vol. 73 Issue 7, p1281-1283, 3p
Publication Year :: 2021
Abstract: Tests for visceral leishmaniasis (VL) are not uniformly effective for all endemic regions. In a serological assay, a novel antigen, otubain cysteine peptidase, compared with rK39, showed comparable sensitivity with Indian VL serum samples and prominently increased sensitivity with Brazilian samples, as well as improved monitoring of the treatment response. [ABSTRACT FROM AUTHOR]

Subjects :: LEISHMANIASIS diagnosis
BIOMARKERS
PREDICTIVE tests
SERODIAGNOSIS
TREATMENT effectiveness
BIOLOGICAL assay
ANTIGENS
EVALUATION

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