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A new ergostane derivative from the leaves of Heynea trijuga Roxburgh.
- Source :
- Natural Product Research; Oct 2021, Vol. 35 Issue 20, p3494-3499, 6p
- Publication Year :
- 2021
-
Abstract
- During the course of searching for structurally interesting and bioactive compounds, a further chemical investigation of the leaves of Heynea trijuga Roxburgh was performed, which led to the isolation of a new ergostane derivative, named 3β, 4β, 20S-trihydroxyergosta-5, 24(28)-dien-16-one (1), together with five known sterides (3β, 23S)-ergosta-5, 24(28)-diene-3, 23-diol (2), ergosta-5, 24(28)-diene-3β-diol (3), stigmast-5-ene-3β, 7α-diol (4), sitoindoside I (5) and stigmast-3β, 5α, 6β-triol (6). The structure of the new compound was elucidated using a combination of 1 D, 2 D NMR techniques and HR-EI-MS analyses. All the compounds were evaluated for cytotoxic activity against tumor cell line BEL-7402 by MTT method. [ABSTRACT FROM AUTHOR]
- Subjects :
- BIOACTIVE compounds
CELL lines
STEROIDS
CURRICULUM
MARINE natural products
COUMARINS
Subjects
Details
- Language :
- English
- ISSN :
- 14786419
- Volume :
- 35
- Issue :
- 20
- Database :
- Complementary Index
- Journal :
- Natural Product Research
- Publication Type :
- Academic Journal
- Accession number :
- 152933939
- Full Text :
- https://doi.org/10.1080/14786419.2020.1712383