Back to Search
Start Over
Efficient Synthesis of α‐Ketothioamides From α‐Nitroketones, Amines or DMF and Elemental Sulfur Under Oxidant‐Free Conditions.
- Source :
- European Journal of Organic Chemistry; 10/7/2021, Vol. 2021 Issue 37, p5209-5212, 4p
- Publication Year :
- 2021
-
Abstract
- We have developed a practical, general protocol for denitration of readily available α‐nitroketones with sulfur and amines to access a broad range of α‐ketothioamides under mild conditions. Such a reaction proceeds under metal‐, oxidant‐, and catalyst‐free conditions to provide synthetically useful α‐ketothioamides. Furthermore, the mild reaction conditions tolerate a wide range of substrates especially for the synthesis of aliphatic α‐ketothioamides which are rarely reported. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 1434193X
- Volume :
- 2021
- Issue :
- 37
- Database :
- Complementary Index
- Journal :
- European Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 153050500
- Full Text :
- https://doi.org/10.1002/ejoc.202100993