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A demographic and clinical panorama of a sixteen-year cohort of soft tissue sarcoma patients in Brazil.

Authors :
de Figueiredo, Luiza Ohasi
Júnior, Augusto Afonso Guerra
de Assis Acurcio, Francisco
Almeida, Alessandra Maciel
Cherchiglia, Mariângela Leal
Wainstein, Alberto Julius Alves
Thuler, Luiz Claudio Santos
Nogueira-Rodrigues, Angélica
Source :
Scientific Reports; 11/18/2021, Vol. 11 Issue 1, p1-11, 11p
Publication Year :
2021

Abstract

Little is known about soft tissue sarcomas (STS) in Brazil, once the federal statistics regarding estimates on incidence and mortality of the most common cancers that affect the Brazilian population currently do not include STS. This study aims to perform a broad evaluation and description of the epidemiological profile, access to treatment and main clinical outcomes of the Brazilian STS patient. A population-based cohort study of 66,825 patients who underwent procedures related to STS treatment registered in the Brazilian public health system (Sistema Único de Saúde, SUS) databases. Median age was 57 years, 30% of them older than 65 years and 50.7% of the cohort was female. The majority, 50,383 patients (75.4%), was diagnosed between 2008 and 2015. Most prevalent anatomic sites were upper and lower limbs (12.6%) and the registry of sarcomas without a specific location comprehended 29.7% of the cohort. The majority of patients resided in the Northeast (40.2% of the patients). Surgery was the first treatment modality in 77.7% of the cases. For survival analysis, only patients with stage and histological grade information were included. The 1-, 5- and 10-year survival rate of the patients was, respectively, 75.4% (95% CI = 74.1–76.7%), 43.4% (95% CI = 41.5–45.5%) and 18.6% (95% CI = 14.8–23.3%). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
20452322
Volume :
11
Issue :
1
Database :
Complementary Index
Journal :
Scientific Reports
Publication Type :
Academic Journal
Accession number :
153651607
Full Text :
https://doi.org/10.1038/s41598-021-02032-5