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Association of substance use disorders and drug overdose with adverse COVID-19 outcomes in New York City: January–October 2020.
- Source :
- Journal of Public Health; 2021 Supplement, Vol. 43, p462-465, 4p
- Publication Year :
- 2021
-
Abstract
- Background Evidence suggests that individuals with history of substance use disorder (SUD) are at increased risk of COVID-19, but little is known about relationships between SUDs, overdose and COVID-19 severity and mortality. This study investigated risks of severe COVID-19 among patients with SUDs. Methods We conducted a retrospective review of data from a hospital system in New York City. Patient records from 1 January to 26 October 2020 were included. We assessed positive COVID-19 tests, hospitalizations, intensive care unit (ICU) admissions and death. Descriptive statistics and bivariable analyses compared the prevalence of COVID-19 by baseline characteristics. Logistic regression estimated unadjusted and sex-, age-, race- and comorbidity-adjusted odds ratios (AORs) for associations between SUD history, overdose history and outcomes. Results Of patients tested for COVID-19 (n  = 188 653), 2.7% (n  = 5107) had any history of SUD. Associations with hospitalization [AORs (95% confidence interval)] ranged from 1.78 (0.85–3.74) for cocaine use disorder (COUD) to 6.68 (4.33–10.33) for alcohol use disorder. Associations with ICU admission ranged from 0.57 (0.17–1.93) for COUD to 5.00 (3.02–8.30) for overdose. Associations with death ranged from 0.64 (0.14–2.84) for COUD to 3.03 (1.70–5.43) for overdose. Discussion Patients with histories of SUD and drug overdose may be at elevated risk of adverse COVID-19 outcomes. [ABSTRACT FROM AUTHOR]
- Subjects :
- INTENSIVE care units
STATISTICS
SUBSTANCE abuse
COVID-19
ACQUISITION of data methodology
ALCOHOLISM
ACADEMIC medical centers
CONFIDENCE intervals
DRUG overdose
RETROSPECTIVE studies
PATIENTS
CATASTROPHIC illness
SEVERITY of illness index
RISK assessment
HOSPITAL admission & discharge
MEDICAL records
HOSPITAL care
COCAINE
DESCRIPTIVE statistics
CHI-squared test
LOGISTIC regression analysis
ODDS ratio
DATA analysis
DATA analysis software
DISEASE risk factors
DISEASE complications
Subjects
Details
- Language :
- English
- ISSN :
- 17413842
- Volume :
- 43
- Database :
- Complementary Index
- Journal :
- Journal of Public Health
- Publication Type :
- Academic Journal
- Accession number :
- 153797691
- Full Text :
- https://doi.org/10.1093/pubmed/fdaa241