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Development of a genomic tool for breed assignment by comparison of different classification models: Application to three local cattle breeds.
- Source :
- Journal of Animal Breeding & Genetics; Jan2022, Vol. 139 Issue 1, p40-61, 22p
- Publication Year :
- 2022
-
Abstract
- Assignment of individual cattle to a specific breed can often not rely on pedigree information. This is especially the case for local breeds for which the development of genomic assignment tools is required to allow individuals of unknown origin to be included to their herd books. A breed assignment model can be based on two specific stages: (a) the selection of breed‐informative markers and (b) the assignment of individuals to a breed with a classification method. However, the performance of combination of methods used in these two stages has been rarely studied until now. In this study, the combination of 16 different SNP panels with four classification methods was developed on 562 reference genotypes from 12 cattle breeds. Based on their performances, best models were validated on three local breeds of interest. In cross‐validation, 14 models had a global cross‐validation accuracy higher than 90%, with a maximum of 98.22%. In validation, best models used 7,153 or 2,005 SNPs, based on a partial least squares‐discriminant analysis (PLS‐DA) and assigned individuals to breeds based on nearest shrunken centroids. The average validation sensitivity of the first two best models for the three local breeds of interest were 98.33% and 97.5%. Moreover, results reported in this study suggest that further studies should consider the PLS‐DA method when selecting breed‐informative SNPs. [ABSTRACT FROM AUTHOR]
- Subjects :
- CATTLE breeding
CATTLE breeds
CLASSIFICATION
GENOTYPES
CENTROID
Subjects
Details
- Language :
- English
- ISSN :
- 09312668
- Volume :
- 139
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Animal Breeding & Genetics
- Publication Type :
- Academic Journal
- Accession number :
- 154103951
- Full Text :
- https://doi.org/10.1111/jbg.12643