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Nef‐specific CD107a+ CD4+ T‐cell responses in a rhesus macaque (Macaca mulatta) showing partial simian immunodeficiency virus control following passive neutralizing antibody infusion.
- Source :
- Journal of Medical Primatology; Feb2022, Vol. 51 Issue 1, p56-61, 6p
- Publication Year :
- 2022
-
Abstract
- Acute‐phase neutralizing antibody (NAb) passive immunization in simian immunodeficiency virus (SIV)‐infected rhesus macaques (Macaca mulatta) can confer stringent viremia control with T‐cell augmentation. In one NAb‐infused SIV partial controller, we identify chronic‐phase Nef‐specific CD107a+ CD4+ T‐cell response maintenance, implicating that NAb infusion modulates long‐term T‐cell responses even within viremic control. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00472565
- Volume :
- 51
- Issue :
- 1
- Database :
- Complementary Index
- Journal :
- Journal of Medical Primatology
- Publication Type :
- Academic Journal
- Accession number :
- 154579668
- Full Text :
- https://doi.org/10.1111/jmp.12551