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Serum uric acid is independently associated with metabolic syndrome and systemic hypertension in women from northeast Brazil.

Authors :
Feitosa, Rafael Silveira
Martins, Beatriz Pereira
Almeida, Lucas Martins
de Oliveira, Max Brandão
de Araújo, Regina Maria Sousa
de Oliveira, Karla Andrade
Source :
Women & Health; Jan 2022, Vol. 62 Issue 1, p68-74, 7p
Publication Year :
2022

Abstract

Hyperuricemia (HU) has been associated with cardiovascular risk and metabolic syndrome (MS) worldwide. However, inconsistencies about this relation are still reported, and it is not clear whether hyperuricemia is an independent risk factor for MS. The aim of this study was to determine hyperuricemia associations with systemic hypertension and MS in women from northeast Brazil. The study included 301 women. Hyperuricemia was considered for serum uric acid (SUA) ≥6 mg/dL. Insulin resistance (IR) was measured by TyG index (TyG ≥ 4.55). Fisher test and Multivariate logistic regression analyses estimated the association between hyperuricemia (or SUA level) and systemic hypertension and MS. Hyperuricemia association with systemic hypertension was independent of age, body-mass index (BMI), smoking and alcoholism (OR: OR: 4.6050; p =.000256), and MS components (OR: 4.1296; IC95% 1.8330_9.3033; p =.000621). Hyperuricemia increased risk of systemic hypertension by 4,6 -fold. SUA level was associated with MS, independently of other classic component factors of the syndrome (OR:1.34, p =.0129). Hyperuricemia and high SUA levels were associated with MS and systemic hypertension. Effect of hyperuricemia in systemic hypertension is independent of age, BMI, lifestyle, and MS factors. SUA levels are independently associated with MS. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
03630242
Volume :
62
Issue :
1
Database :
Complementary Index
Journal :
Women & Health
Publication Type :
Academic Journal
Accession number :
154691252
Full Text :
https://doi.org/10.1080/03630242.2021.2019170