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Defining high‐risk elective contralateral neck radiation volumes for oropharynx cancer.
- Source :
- Head & Neck; Feb2022, Vol. 44 Issue 2, p317-324, 8p
- Publication Year :
- 2022
-
Abstract
- Background: To define the location of the initial contralateral lymph node (LN) metastasis in patients with oropharynx cancer. Methods: The location of the LN centroids from patients with oropharynx cancer and a single radiographically positive contralateral LN was defined. A clinical target volume (CTV) inclusive of all LN centroids was created, and its impact on dose to organs at risk was assessed. Results: We identified 55 patients of which 49/55 had a single contralateral LN in level IIA, 4/55 in level III, 1/55 in level IIB, and 1/55 in the retropharynx. Mean radiation dose to the contralateral parotid gland was 15.1 and 21.0 Gy, (p <0.001) using the modeled high‐risk elective CTV and a consensus CTV, respectively. Conclusions: We present a systematic approach for identifying the contralateral nodal regions at highest risk of harboring subclinical disease in patients with oropharynx cancer that warrants prospective clinical study. [ABSTRACT FROM AUTHOR]
- Subjects :
- OROPHARYNX
PAROTID glands
NECK
LYMPH nodes
CANCER patients
HEAD & neck cancer
Subjects
Details
- Language :
- English
- ISSN :
- 10433074
- Volume :
- 44
- Issue :
- 2
- Database :
- Complementary Index
- Journal :
- Head & Neck
- Publication Type :
- Academic Journal
- Accession number :
- 154715734
- Full Text :
- https://doi.org/10.1002/hed.26924