Histopathological prognostic factors in patients with cervical cancer treated with radical hysterectomy and postoperative radiotherapy.

The article analyzes histopathological prognostic factors. One hundred and thirty patients with stage I-II uterine cervical cancer were treated with radical hysterectomy and postoperative radiotherapy at Ehime University Hospital between 1978 and 1997. All surgical specimens were reviewed, and the relationship between histopathological factors and the clinical outcome was analyzed. Significant differences in prognosis were observed for six factors: pT factor, venous infiltration, pelvic lymph node metastases, thickness of the residual muscular layer, tumor depth, and tumor growth pattern. The risk classification may make it possible to predict which patients are at risk of recurrence.