Staphylococcus aureuscell-envelope antigens are localized in glomeruli from patients with IgA-related nephropathy.

The article reports that staphylococcus aureuscell-envelope antigens are localized in glomeruli from patients with IgA-related nephropathy. Staphylococcus aureus (S. aureus) is a common, normal, and pathogenic flora that colonizes on mucosal tissues. Western blotting analysis showed that the monoclonal antibody reacted with 35 kDa of S. aureus antigens. Histopathological examination was performed in 130 patients with IgA-related nephropathy and 108 patients with other renal diseases using antibodies originated from patients' sera and mouse monoclonal antibody against S. aureus cell membrane antigens.